原著論文(欧文) | 院長の業績紹介 | 北浜 なにわ橋 淀屋橋 至近の皮膚科『あずきざわ皮ふ科』
北浜、なにわ橋、淀屋橋至近の皮膚科『あずきざわ皮ふ科』です。アトピー、じんましん、薬疹、血管性浮腫をはじめとしたアレルギーや、にきび、ヘルペス、乾癬、 水疱症、いぼなど、幅広い皮膚疾患に対応いたします。

原著論文(欧文)

  • Mitsui Y, Ogawa K, Fukumoto T, Sasaki C, Sonobe H, Azukizawa H, Koga K, Asada H. Superficial sebaceous carcinoma: The correlations between the clinical, dermoscopic and histopathological findings of a rare variant of sebaceous carcinoma. J Dermatol. 2019 [Epub ahead of print]
  • Iwasa K, Ogawa K, Azukizawa H, Tanabe H, Iwanaga T, Anzawa K, Mochizuki T, Asada H. Revival of favus in Japan caused by Trichophyton schoenleinii. J Dermatol. 2019 Apr;46(4):347-350.
  • Ogawa K, Mitsui Y, Miyamoto S, Nakamura-Nishimura Y, Nakanishi Y, Azukizawa H, Asada H. Facial pustules due to drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms may histopathologically mimic eosinophilic pustular folliculitis: A case report. J Cutan Pathol. 2019 May;46(5):363-367
  • Tashiro Y, Azukizawa H, Asada H, Niihara H, Morita E, Yamauchi T, Mizukawa Y, Kusakabe Y, Numazawa S, Izumi M, Sueki H, Watanabe H. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms due to lamotrigine differs from that due to other drugs. J Dermatol. 2019 Mar;46(3):226-233.
  • Miyagawa F, Azukizawa H, Mimori T, Asada H. Anti-PL-12 antibody-positive antisynthetase syndrome with recurrent digital ulcers. J Dermatol. 2019 Apr;46(4):e143-e145.
  • Mitsui Y, Ogawa K, Takeda M, Nakanishi T, Azukizawa H, Asada H. First Japanese case of atypical Spitz tumor exhibiting ROS1 rearrangement. J Dermatol. 2018 Sep;45(9):e248-e249.
  • Miyashita K, Miyagawa F, Nakamura Y, Ommori R, Azukizawa H, Asada H. Up-regulation of Human Herpesvirus 6B-derived microRNAs in the Serum of Patients with Drug-induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms. Acta Derm Venereol. 2018 Jun 8;98(6):612-613.
  • Shobatake C, Miyagawa F, Ogawa K, Azukizawa H, Hirai T, Kuwahara M, Asada H. Preoperative assessment of tumour thickness and vascularity using high-frequency ultrasonography in ten cases of cutaneous melanoma. Eur J Dermatol. 2018 Apr 1;28(2):256-258.
  • Ono A, Azukizawa H, Ito S, Nakamura Y, Asada H, Quan YS, Kamiyama F, Katayama I, Hirobe S, Okada N. Development of novel double-decker microneedle patches for transcutaneous vaccine delivery. Int J Pharm. 2017 Oct 30;532(1):374-383.
  • Murota H, Azukizawa H, Katayama I. Impact of Jumihaidokuto (Shi-Wei-Bai-Du-Tang) on treatment of chronic spontaneous urticaria: A randomized controlled study. Chin J Integr Med. 2017 Aug 17.
  • Ogawa K, Fukumoto T, Azukizawa H, Takeda M, Asada H. First Japanese case report of atypical Spitz tumor with an ALK rearrangement. J Dermatol. 2017 Dec;44(12):e342-e343.
  • Kato K, Kawase A, Azukizawa H, Hanafusa T, Nakagawa Y, Murota H, Sakaguchi S, Asada H, Katayama I. Novel interferon-γ enzyme-linked immunoSpot assay using activated cells for identifying hypersensitivity-inducing drug culprits. J Dermatol Sci. 2017 Jun;86(3):222-229. doi: 10.1016/j.jdermsci.2017.03.007.
  • Ardouin L, Luche H, Chelbi R, Carpentier S, Shawket A, Montanana Sanchis F, Santa Maria C, Grenot P, Alexandre Y, Grégoire C, Fries A, Vu Manh TP, Tamoutounour S, Crozat K, Tomasello E, Jorquera A, Fossum E, Bogen B, Azukizawa H, Bajenoff M, Henri S, Dalod M, Malissen B. Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery. Immunity. 2016 Aug 16;45(2):305-1
  • Hanafusa T, Kato K, Azukizawa H, Miyazaki J, Takeda J, Katayama I. B-1 B cell progenitors transiently and partially express keratin 5 during differentiation in bone marrow. J Dermatol Sci. 2016 Mar;81(3):173-81.
  • Yamaoka T, Inoue T, Kitaba S, Yokomi A, Azukizawa H, Terao M, Murota H, Higashiyama M, Katayama I. Psoriatic Arthritis Complicating Systemic Sclerosis: Possible Involvement of M2 Macrophages. Ann Dermatol. 27(5):631-2. 2015
  • Inoue-Nishimoto T, Hanafusa T, Igawa K, Azukizawa H, Yokomi A, Yokozeki H, Katayama I. Possible association of anti-tumor necrosis factor-α antibody therapy with the development of scleroderma-like changes with lichen planus. Eur J Dermatol. 1;25(5):513-5. 2015
  • Aihara M, Kano Y, Fujita H, Kambara T, Matsukura S, Katayama I, Azukizawa H, Miyachi Y, Endo Y, Asada H, Miyagawa F, Morita E, Kaneko S, Abe R, Ochiai T, Sueki H, Watanabe H, Nagao K, Aoyama Y, Sayama K, Hashimoto K, Shiohara T; Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis.SJS/TEN Study Group. J Dermatol. 42(8):768-77 2015
  • Hirobe S, Azukizawa H, Hanafusa T, Matsuo K, Quan YS, Kamiyama F, Katayama I, Okada N, Nakagawa S. Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch. Biomaterials. 57:50-8. 2015
  • Baratin M, Foray C, Demaria O, Habbeddine M, Pollet E, Maurizio J, Verthuy C, Davanture S, Azukizawa H, Flores-Langarica A, Dalod M, Lawrence T. Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance. Immunity. 42(4):627-39 2015
  • Kano Y, Tohyama M, Aihara M, Matsukura S, Watanabe H, Sueki H, Iijima M, Morita E, Niihara H, Asada H, Kabashima K, Azukizawa H, Hashizume H, Nagao K, Takahashi H, Abe R, Sotozono C, Kurosawa M, Aoyama Y, Chu CY, Chung WH, Shiohara T. J Dermatol. Sequelae in 145 patients with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: Survey conducted by the Asian Research Committee on Severe Cutaneous Adverse Reactions (ASCAR). J. Dermatol. 42(3):276-82. 2015
  • Hashimoto N, Yamaoka T, Koguchi-Yoshioka H, Tanaka A, Tanemura A, Azukizawa H, Murota H, Kang J, Nakagawa Y, Shimazu T, Katayama I. Development of Necrotising Fasciitis in a Patient Treated for Rheumatoid Arthritis with Tocilizumab.Acta Derm Venereol. 9;95(3):370-371. 2015
  • Chung WH, Chang WC, Lee YS, Wu YY, Yang CH, Ho HC, Chen MJ, Lin JY, Hui RC, Ho JC, Wu WM, Chen TJ, Wu T, Wu YR, Hsih MS, Tu PH, Chang CN, Hsu CN, Wu TL, Choon SE, Hsu CK, Chen DY, Liu CS, Lin CY, Kaniwa N, Saito Y, Takahashi Y, Nakamura R, Azukizawa H, Shi Y, Wang TH, Chuang SS, Tsai SF, Chang CJ, Chang YS, Hung SI Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. JAMA. 6;312(5):525-34. 2014
  • Yamaga K, Hanafusa T, Azukizawa H, Tanemura A, Nii T, Nishide M, Narazaki M, Katayama I. Immune reconstitution inflammatory syndrome in a patient with adult-onset Still’s disease: graft-versus-host-like skin reaction with possible asymptomatic human herpes virus reactivation during steroid tapering. Eur J Dermatol. 24(1):101-3. 2014
  • Hirobe S, Azukizawa H, Matsuo K, Zhai Y, Quan YS, Kamiyama F, Suzuki H, Katayama I, Okada N, Nakagawa S. Development and clinical study of a self-dissolving microneedle patch for transcutaneous immunization device. Pharm Res. 30(10):2664-74. 2013
  • Nakajima K, Terao M, Takaishi M, Kataoka S, Goto-Inoue N, Setou M, Horie K, Sakamoto F, Ito M, Azukizawa H, Kitaba S, Murota H, Itami S, Katayama I, Takeda J, Sano S. Barrier Abnormality Due to Ceramide Deficiency Leads to Psoriasiform Inflammation in a Mouse Model. J Invest Dermatol. 133(11):2555-65. 2013
  • Yamaoka T, Azukizawa H, Tanemura A, Murota H, Hirose T, Hayakawa K, Shimazu T, Wada N, Morii E, Katayama I. Toxic epidermal necrolysis complicated by sepsis, haemophagocytic syndrome, and severe liver dysfunction associated with elevated interleukin-10 production. Eur J Dermatol. 22(6):815-7. 2012
  • Hanafusa T, Azukizawa H, Nishioka M, Tanemura A, Murota H, Yoshida H, Sato E, Hashii Y, Ozono K, Koga H, Hashimoto T, Katayama I. Lichen planus-type chronic graft-versus-host disease complicated by mucous membrane pemphigoid with positive anti-BP180/230 and scleroderma-related autoantibodies followed by reduced regulatory T cell frequency. Eur J Dermatol. 22(1):140-2. 2012
  • Hanafusa T, Azukizawa H, Matsumura S, Murakami Y, Tanaka A, Kurachi K, Katayama I. Non-pigmenting fixed drug eruption caused by an over-the-counter non-steroidal anti-inflammatory drug: drug-specific CD8+ T lymphocytes identified in peripheral blood. Eur J Dermatol. 22(5):680-2. 2012
  • Kitaba S, Murota H, Terao M, Azukizawa H, Terabe F, Shima Y, Fujimoto M, Tanaka T, Naka T, Kishimoto T, Katayama I. Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma. Am J Pathol. ;180(1):165-76. 2012
  • Hanafusa T, Yoshioka E, Azukizawa H, Itoi S, Tani M, Kira M, Katayama I. Systemic allergic contact dermatitis to palladium inlay manifesting as annular erythema. Eur J Dermatol. 22(5):697-8. 2012
  • Hanafusa T, Azukizawa H, Matsumura S, Katayama I. The predominant drug-specific T-cell population may switch from cytotoxic T cells to regulatory T cells during the course of anticonvulsant-induced hypersensitivity. J Dermatol Sci. 65(3):213-9. 2012
  • Crozat K, Tamoutounour S, Manh TP, Fossum E, Luche H, Ardouin L, Guilliams M, Azukizawa H, Bogen B, Malissen B, Henri S, Dalod M  Cutting edge: Expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.  J Immunol. 1;187(9):4411-5, 2011
  • Hanafusa T, Azukizawa H, Kitaba S, Murota H, Umegaki N, Terao M, Sano S, Nakagiri T, Okumura M, Katayama I. Diminished regulatory T cells in cutaneous lesions of thymoma-associated multi-organ autoimmunity: a newly described paraneoplastic autoimmune disorder with fatal clinical course. Clin Exp Immunol. 166(2):164-70. 2011
  • Hanafusa T, Igawa K, Azukizawa H, Katayama I. Acute generalized exanthematous pustulosis induced by topical diphenhydramine. Eur J Dermatol. 21(6):994-5. 2011
  • Azukizawa H, Döhler A, Kanazawa N, Nayak A, Lipp M, Malissen B, Autenrieth I, Katayama I, Riemann M, Weih F, Berberich-Siebelt F, Lutz MB.  Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells. Eur J Immunol. 41(5):1420-34, 2011
  • Murakami Y, Wataya-Kaneda M, Terao M, Azukizawa H, Murota H, Nakata Y, Katayama I. Peculiar distribution of tumorous xanthomas in an adult case of erdheim-chester disease complicated by atopic dermatitis. Case Rep Dermatol.;3(2):107-12. 2011
  • Hanafusa T, Azukizawa H, Umegaki N, Tani M, Yamaguchi Y, Katayama I. Clinical implications of leukocytapheresis using a centrifugal cell separator for steroid-resistant pyoderma gangrenosum associated with inflammatory bowel disease. J Dermatol. 38(5):507-10. 2011
  • Hanafusa T, Azukizawa H, Kitaba S, Murota H, Umegaki N, Terao M, Sano S, Nakagiri T, Okumura M, Katayama I. Impact of sedative and non-sedative antihistamines on the impaired productivity and quality of life in patients with pruritic skin diseases. Allergol Int. 59(4):345-54 2010
  • Henri S, Poulin LF, Tamoutounour S, Ardouin L, Guilliams M, de Bovis B, Devilard E, Viret C, Azukizawa H, Kissenpfennig A, Malissen B.  CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells. J Exp Med. 18;207(1):189-206. 2010
  • Broom JK, Lew AM, Azukizawa H, Kenna TJ, Leggatt GR, Frazer IH. Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes. J Invest Dermatol. 130(6):1581-9. 2010
  • De Kluyver RL, Moritz L, Harris CA, Azukizawa H, Frazer IH. Antigen-specific CD8 T cells can eliminate antigen-bearing keratinocytes with clonogenic potential via an IFN-gamma-dependent mechanism. J Invest Dermatol. 130(7):1841-8. 2010
  • Kitaba S, Murota H, Yahata Y, Azukizawa H, Katayama I. Novel functional aspect of antihistamines: the impact of bepotastine besilate on substance p-induced events. J Allergy (Cairo). 2009
  • Inui S, Azukizawa H, Katayama I. Recurrent contact cheilitis because of glyceryl isostearate, diisostearyl maleate, oleyl alcohol, and Lithol Rubine BCA in lipsticks. Contact Dermatitis. 60(4):231-2. 2009
  • Waithman J, Allan RS, Kosaka H, Azukizawa H, Shortman K, Lutz MB, Heath WR, Carbone FR, Belz GT.  Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells  J Immunol  1;179(7):4535-41 2007
  • Sumikawa Y, Asada H, Hoshino K, Azukizawa H, Katayama I, Akira S, Itami S. Induction of beta-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2.Microbes Infect. 8(6):1513-21. 2006
  • Inui S, Azukizawa H, Asada H, Itami S. Amicrobial pustulosis with antinuclear antibodies and rheumatoid factor. Br J Dermatol. 154(3):568-9. 2006
  • Azukizawa H, Sano S, Kosaka H, Sumikawa Y, Itami S. Prevention of toxic epidermal necrolysis by regulatory T cells. Eur J Immunol. 35(6):1722-30. 2005
  • Asada H, Miyagawa S, Tamura M, Azukizawa H, Tanemura A, Yamaguchi Y, Sumikawa Y, Itami S, Kubo T, Yoshikawa K. Evaluation of provocation test monitoring palmoplantar temperature with the use of thermography for diagnosis of focal tonsillar infection in palmoplantar pustulosis. J Dermatol Sci.32(2):105-13. 2003
  • Azukizawa H, Kosaka H, Sano S, Heath WR, Takahashi I, Gao XH, Sumikawa Y, Okabe M, Yoshikawa K, Itami S. Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes. Eur J Immunol. 33(7):1879-88. 2003
  • Takahashi I, Kosaka H, Oritani K, Heath WR, Ishikawa J, Okajima Y, Ogawa M, Kawamoto S, Yamada M, Azukizawa H, Itami S, Yoshikawa K, Tomiyama Y, Matsuzawa Y. A new IFN-like cytokine, limitin, modulates the immune response without influencing thymocyte development. J Immunol. 15;167(6):3156-63. 2001
  • Sano S, Itami S, Azukizawa H, Araki Y, Higashiyama M, Yoshikawa K. Interleukin 5-inducing activity in the blister fluid of eosinophilic pustular dermatosis. Br J Dermatol. 141(1):154-5. 1999
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あずきざわ皮ふ科
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  • アレルギー科
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